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cheap, but desirable: generic drugs a great alternative to the brand name for hypertension

hypertension, generic drugs could be so good that an option as a brand medication is there, while it costs only half as much, the study suggests

image: Studying shows that generic hypertension drugs could be as good as their fire name counterparts when lowering blood pressure over the long-term view more

Credit: Chinese Medical Journal

Hypertension is a common disease and a primary cause of cardiovascular diseases and lighters worldwide. Unfortunately, Professor Wei-Li Zhang of the Chinese National Center for Cardiovascular Diseases Notes, "The unnecessary liability of medicines is an important barrier for medication liability in patients living in low and medium-sized income areas."

One of the countries where hypertension becomes an important problem is China, where researchers live between 244 million and 300 million adults with hypertension. But faithful to the words of Prof. Zhang, most cases of hypertension in China are not sufficiently controlled, and patients looking for the treatment of hypertension must pay for outpatient clinic visits and carry drug costs out of the pocket.

An emerging option to control the costs of antihypertensive pharmacotherapy is to prescribe generic drugs that have the same active ingredients that have their brand names, but much less costs. Several countries have taken steps to promote the prescription of generic drugs as a way of reducing health expenditure and reducing more patients, but some clinicians have reservations to generics due to concern that such drugs are not as effective as their brand names Colleagues. Another team of researchers conducted by Prof. Zhang decided to carry out an investigation to determine whether generic antihypertensive medicines are generally present as fire name drugs to control blood pressure in the control of blood pressure. Your results appear in a recently published paper Chinese Medical Journal .

In her study, she analyzed data from a cohort study of patients with hypertension, which was carried out in 12 Chinese provinces in 12 hospitals. The baseline screenings have occurred between 2013 and 2015, and follow-up assessments continued until 1 August 2017. The researchers focused on 2,176 students who used brand namen-antihypertensive medications and 4,352 participants generated generated generic drugs. They performed statistical analyzes to compare the two groups in relation to blood pressure changes over the follow-up period.

They found that generic drugs were just as effective as brand medications to reduce blood pressure. Between the group with generic drugs and the use of fire name drugs, with the percentages of patients who achieved a well-controlled blood pressure levels (defined here as systolic blood pressure below 140 mmHg and diastolic blood pressure below 90 mmHg) and the probabilities Experience cardiovascular results like coronary heart disease and stroke were similar. After adaptation by age, sex, body mass index values, the number of antihypertensive microns, and traditional cardiovascular risk factors, was the mean reduction of systolic blood pressure 7.9 mmHg for participants, the brand medications and 7.1 mmHg for participants assumed Were generic drugs.

However, some differences in the results arise when the researchers examined certain subscriber subscribers. Among the participants who were younger than 60 years old were those who took brand medications were more likely to achieve a well-controlled blood pressure level than their colleagues who had taken generic drugs. A similar difference between brand medications and generic drugs was created when the investigators restricted their analyzes to men with high blood pressure.

Despite the differences observed in the subgroup analyzes, the results provide overall strong evidence for generic drugs, which are just as effective as they are as effective to lower the blood pressure mirror. It is important that the generic drugs are these effects with much lower cost to reach; A 1 mmHg reduction of systolic blood pressure proved to be 315.40 USD with generic drugs than with fire names. This cost difference means that treatment with generic drugs is only half as expensive as treatment with brand name drugs, and this will undoubtedly mean a lot with the many people in China and beyond, which is beyond low to medium-sized income.

Therefore, Prof. Zhang expresses that these findings "provide a pulse for physicians and patients to preferably use generic drugs instead of expensive brand medications to reduce blood pressure levels." By expanding access to antihypertensive treatment, the use of generic drugs of public health in China and other developing countries will provide important benefits.

Title of Original Papers: Rating of the Blood Pressure Reduction Effect by Generic and Brand Name Antihypertensive Drug Treatment: A diverse prospective study in China

Journal: Chinese medical journal

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